Hiding at a hotel, the deformed man returns, revealing himself as Junior Roark, disfigured by years of surgery to regenerate his body parts. He realizes he was set up to lead the yellow man to Nancy and the two escape in Nancy's car. He eventually finds her at Kadie's Bar, where she has become an exotic dancer. Hartigan confesses to all charges leading to his parole and searches for an adult Nancy (Jessica Alba), not knowing he is being followed by a deformed, yellow man. After eight years, the letters stop and he receives a severed finger instead.

He receives a weekly letter from Nancy, as promised. Hartigan goes to jail, though he refuses to confess. A grateful Nancy promises to write letters every week while he is in prison. Hartigan will be framed for Junior's crimes if he tells anyone the truth, they will die. Hartigan is recovering in a hospital when Senator Roark informs him that Junior is in a coma and the Roark legacy is in serious jeopardy. Hartigan passes out, reasoning his death is a fair trade for the girl's life. As police backup approaches, Bob leaves and Nancy lies down in Hartigan's lap. Bob, now recovered, shoots Hartigan in the back. Hartigan catches up and shoots off Junior's ear, hand, and genitals. Junior shoots Hartigan in the shoulder and tries to escape. Hartigan heads into the warehouse where Roark Junior is holding Nancy, fighting off the pain caused by his bad heart, as well as several henchmen. Hartigan's corrupt partner, Bob (Michael Madsen) tries to convince Hartigan to walk away. Junior is the son of Senator Roark (Powers Boothe), who has bribed the police to cover up his son's crimes. On the docks of Sin City, aging police officer John Hartigan (Bruce Willis) tries to stop serial child-killer Roark Junior (Nick Stahl) from raping and killing his fourth known victim, eleven-year-old Nancy Callahan (Makenzie Vega).

Rutger Hauer as Cardinal Patrick Henry Roark.The movie is based on 4 stories from the Sin City universe including:

Sin city miller